Detalhe da pesquisa
1.
The NADH recycling enzymes TsaC and TsaD regenerate reducing equivalents for Rieske oxygenase chemistry.
J Biol Chem
; 299(10): 105222, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37673337
2.
Pathways of thymidine hypermodification.
Nucleic Acids Res
; 50(6): 3001-3017, 2022 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34522950
3.
High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J Biol Chem
; 298(10): 102454, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36063993
4.
Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J Biol Chem
; 297(1): 100823, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34029591
5.
Structure and function of the two-component flavin-dependent methanesulfinate monooxygenase within bacterial sulfur assimilation.
Biochem Biophys Res Commun
; 522(1): 107-112, 2020 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31753487
6.
Structural elements of an NRPS cyclization domain and its intermodule docking domain.
Proc Natl Acad Sci U S A
; 113(44): 12432-12437, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791103
7.
Molecular basis of cobalamin-dependent RNA modification.
Nucleic Acids Res
; 44(20): 9965-9976, 2016 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638883
8.
7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J Am Chem Soc
; 139(5): 1912-1920, 2017 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28045519
9.
Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
Nat Chem Biol
; 10(2): 106-12, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24362703
10.
Structural diversity in the AdoMet radical enzyme superfamily.
Biochim Biophys Acta
; 1824(11): 1178-95, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579873
11.
Dynamics and mechanistic interpretations of nonribosomal peptide synthetase cyclization domains.
Curr Opin Chem Biol
; 72: 102228, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36402006
12.
Global protein dynamics as communication sensors in peptide synthetase domains.
Sci Adv
; 8(28): eabn6549, 2022 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857508
13.
Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases.
J Am Chem Soc
; 133(32): 12474-7, 2011 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21790156
14.
Synthesis of a new trifluoromethylketone analogue of l-arginine and contrasting inhibitory activity against human arginase I and histone deacetylase 8.
Bioorg Med Chem Lett
; 21(19): 5854-8, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21875805
15.
Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function .
Biochemistry
; 49(24): 5048-56, 2010 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20545365
16.
Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Biochemistry
; 49(26): 5600-8, 2010 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20527960
17.
Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
Protein Sci
; 28(1): 202-215, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30341796
18.
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Biochemistry
; 47(51): 13554-63, 2008 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19053282
19.
Radical use of Rossmann and TIM barrel architectures for controlling coenzyme B12 chemistry.
Annu Rev Biophys
; 41: 403-27, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22577824
20.
Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes.
Curr Opin Struct Biol
; 21(6): 735-43, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21872466